This blog post was prepared by PLOS One Senior Editor Joanna Tindall. The Anthropocene is a geological epoch defined by human actions…
Telemedicine Research Highlights: Advancing Access and Equity in Patient Care
Close-up of a doctor using a laptop, wearing a stethoscope and white coatThis blog post was prepared by PLOS One Associate Editor Katherine Kokkinias.
As telemedicine becomes more ubiquitous in healthcare across the globe, so has research evaluating these interventions. From 2011 to 2025, PLOS One has published an increasing volume of telemedicine manuscripts over time. During this period, there were 1,955 telemedicine manuscripts published, amassing over 56,500 citations. Notably, we have seen an acceleration of telemedicine utilization and telemedicine research post-COVID-19. (Figure 1) (1).
In this blog, we highlight a subset of PLOS One articles published between 2011 and 2025 that emphasize the benefits and challenges that arise when implementing telemedicine. These publications offer practical solutions to improve and evaluate telemedicine interventions with the goal of expanding access to care and health equity among vulnerable communities. Furthermore, the articles underscore the necessity of having health equity and sustainability at the forefront of design, telemedicine policy, and telemedicine implementation efforts. Please enjoy this collection of articles.

Figure 1: Number of telemedicine publications at PLOS One from 2011 to 2025.This figure was generated using data obtained on June 11, 2026, from Digital Science’s Dimensions platform, available at https://app.dimensions.ai.
Maternal telehealth care may benefit more from basic digital infrastructure than sophisticated technological solutions
When examining the landscape of information and communication technologies in Latin American and Caribbean countries, Capasso and colleagues identified disparities in access to digital health persist in remote and rural communities particularly, with limitations in digital infrastructure (2). The main facilitators in adoption of digital health were provider training and availability of adequate equipment, internet, and technology. Often, telemedicine is thought to require complex digital platforms to increase healthcare access, but this study suggests that investing in universal digital coverage may be a more sustainable solution to improve telehealth access for reproductive care in remote and rural communities.
Telemedicine improves access to health information while improving patient satisfaction during routine HIV care
As new tools and interventions in telemedicine are developed, there is a need to evaluate their efficacy compared to standard care alone. In their mixed methods clinical trial from 2011, León and colleagues evaluated a telemedicine tool their team created, Virtual Hospital platform, which includes virtual consultations, telepharmacy, a virtual library and virtual community (3). While clinical and quality of life parameters were similar between those with the telemedicine intervention and those without the intervention, there was high technical satisfaction among users and providers, giving patients direct access to their medical results and health information. This forward-thinking clinical trial demonstrates how telemedicine can be used to improve access to providers, resources, and medical information at a time when individual internet access and the movement towards electronic health records was increasing globally.
COVID-19 illustrates the importance of considering health equity when implementing telemedicine
With the roll-out of telemedicine, it is vital to evaluate equitable access across different populations, especially during a pandemic. Here Khatana and colleagues utilized real-world data to identify patterns in sociodemographic characteristics of patients who had at least one telemedicine encounter during the study period (4). They identified that there were differences in utilization across different sub-groups, with lower odds of receiving telemedicine among older, male, and non-Hispanic Black patients. These findings help us understand disparities in access across different groups and in different regions, which can be leveraged to improve equitable availability of telemedicine by targeting intervention efforts.
Telephone support and telemonitoring significantly reduced the odds of deaths and hospitalization due to heart failure compared to usual care
With the growth of telemedicine research, systematic reviews can be a valuable tool to evaluate telemedicine interventions. In their systematic review, Kotb and colleagues compare the impact of different telemedicine options for heart failure (5). Specifically, the authors compared telephone support, telemonitoring, video monitoring or electrocardiographic monitoring among patients with heart failure. Synthesizing the findings of 30 randomized controlled trials, they found that telephone support and telemonitoring significantly reduced the odds of deaths and hospitalization due to heart failure compared to usual care. Systematic reviews and meta-analysis manuscripts, such as the one described here, help lawmakers assess the impact of telemedicine on health outcomes to generate policy and direct implementation efforts. This work has been cited in several policy documents generated by the Norwegian Institute of Public Health and the Organisation for Economic Co-operation and Development (OECD) (6-7).
References
- Digital Science. (2018–). Dimensions [Software]. Available from https://app.dimensions.ai. Accessed on June 11th, 2026.
- Capasso A, Colomar M, Ramírez D, Serruya S, de Mucio B (2024) Digital health and the promise of equity in maternity care: A mixed methods multi-country assessment on the use of information and communication technologies in healthcare facilities in Latin America and the Caribbean. PLoS ONE 19(2): e0298902. https://doi.org/10.1371/journal.pone.0298902
- León A, Cáceres C, Fernández E, Chausa P, Martin M, Codina C, et al. (2011) A New Multidisciplinary Home Care Telemedicine System to Monitor Stable Chronic Human Immunodeficiency Virus-Infected Patients: A Randomized Study. PLoS ONE 6(1): e14515. https://doi.org/10.1371/journal.pone.0014515
- Khatana SAM, Yang L, Eberly LA, Julien HM, Adusumalli S, Groeneveld PW (2022) Predictors of telemedicine use during the COVID-19 pandemic in the United States–an analysis of a national electronic medical record database. PLoS ONE 17(6): e0269535. https://doi.org/10.1371/journal.pone.0269535
- Kotb A, Cameron C, Hsieh S, Wells G (2015) Comparative Effectiveness of Different Forms of Telemedicine for Individuals with Heart Failure (HF): A Systematic Review and Network Meta-Analysis. PLoS ONE 10(2): e0118681. https://doi.org/10.1371/journal.pone.0118681
- Meneses-Echavez, J. F., Johansen, T. B., Holte, H. H., Harboe, I., Underland, V., & Zinöcker, S. (2022). Remote patient monitoring and resource use in the specialized health service: An overview of systematic reviews (revised edition). Norwegian Institute of Public Health.
- OECD (2023), Integrating Care to Prevent and Manage Chronic Diseases: Best Practices in Public Health, OECD Publishing, Paris, https://doi.org/10.1787/9acc1b1d-en.